Genkwadaphnin
Product Specifications
CAS Number
55073-32-0
Bioactivity
Genkwadaphnin, a daphnane diterpenoid, targets importin-?1, reducing the nuclear accumulation of CRPC drivers and suppressing downstream oncogenic signaling. Demonstrating potent anti-tumor effects, it inhibits castration-resistant prostate cancer (CRPC) in vivo in mice [1].
Smiles
C[C@H]1[C@]23[C@]([C@@]4([C@](C(C)=C)([C@@H]1OC(=O)C5=CC=CC=C5)O[C@](O2)(O4)C6=CC=CC=C6)[H])([C@]7([C@](CO)(O7)[C@@H](O)[C@@]8(O)[C@]3(C=C(C)C8=O)[H])[H])[H]
Molecular Formula
C34H34O10
Molecular Weight
602.63
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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