GTPγS tetralithium
Product Specifications
CAS Number
94825-44-2
Target
Others, transporter
Related Pathways
Others, Metabolism
Purity
0.75
Bioactivity
GTPγS tetralithium (Guanosine 5'-[γ-thio]triphosphate tetralithium) is a G-protein activator, a non-hydrolyzable GTP analog that protects proteins from proteolytic degradation.GTPγS tetralithium is involved in the detection of cells expressing recombinant receptors and endogenous receptors. GTPγS tetralithium is involved in the detection of GPCR signaling in cells expressing recombinant receptors as well as in cells and tissues expressing endogenous receptors, and can be assayed to measure agonist-induced desensitization of two human polymorphic α2B-adrenoceptor variants.
Smiles
O[C@H]1[C@@H](O[C@@H]([C@H]1O)COP(OP(OP([O-])([S-])=O)([O-])=O)([O-])=O)N2C3=C(C(N=C(N3)N)=O)N=C2.[Li+].[Li+].[Li+].[Li+]
Molecular Formula
C10H12Li4N5O13P3S
Molecular Weight
562.98
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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