What is the catalog number for ICMT-IN-35?

The catalog number for ICMT-IN-35 is T82108.

What sizes are available for ICMT-IN-35?

ICMT-IN-35 is available in the following size(s): 5 mg, 50 mg.

How many pack sizes does ICMT-IN-35 come in?

ICMT-IN-35 is available in 2 different pack sizes.

Is ICMT-IN-35 in stock?

ICMT-IN-35 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures ICMT-IN-35?

ICMT-IN-35 is manufactured by Molfinity.

What is the estimated delivery time for ICMT-IN-35?

Estimated delivery time for ICMT-IN-35 is approximately 10 business day(s), depending on your location.

ICMT-IN-35

Product Specifications

Target

Others, Transferase

Related Pathways

Metabolism, Others

Bioactivity

ICMT-IN-35 (compound 10n), an ICMT inhibitor with an IC50 value of 0.8 μM, is a FTPA-triazole derivative. It demonstrates cellular uptake by mammalian cells, disrupts K-Ras membrane association, and induces K-Ras mislocalization. Additionally, ICMT-IN-35 exhibits selective cytotoxicity towards ICMT +/+ MEF cells and possesses potent activity against metastatic pancreatic cancer cell lines with an IC 50 of 0.8 μM [1].