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ICMT-IN-54

Product Specifications

CAS Number

908856-14-4

Target

Others, Transferase

Related Pathways

Metabolism, Others

Bioactivity

ICMT-IN-54 (compound 7c), an adamantyl analogue, serves as an ICMT inhibitor with an IC50 value of 12.4 μM, targeting the methylation process facilitated by ICMT. It specifically inhibits the methylation of BFC (N-biotinyl- (6-aminohexanoic) -S-farnesyl-L-cysteine) in Saccharomyces cerevisiae expressing ICMT, marking an indirect inhibition of ICMT-mediated methylation [1].

Smiles

C(N[C@@H](CSC/C=C(/CC/C=C(/CCC=C(C)C)\C)\C)C(O)=O)(=O)C12CC3CC(C1)CC(C2)C3

Molecular Formula

C29H45NO3S

Molecular Weight

487.74

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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