IGRP (206-214)

IGRP (206-214) is an bioactive peptide corresponding to residues 206–214 of the murine islet-specific glucose-6-phosphatase catalytic subunit–related protein (IGRP) . It induces diabetes in non-obese diabetic (NOD) mice by being specific for T cells targeting both proinsulin and IGRP.

[C@@H](CC1=CC=CC=C1)(NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC2=CC=C(O)C=C2)NC([C@H](C(C)C)N)=O)=O)CC(C)C)=O)CCCCN)=O)[C@@H](C)O)=O)CC(N)=O)=O)C(C)C)=O)C(N[C@@H](CC(C)C)C(O)=O)=O