KPZ560
Product Specifications
CAS Number
2397562-43-3
Target
HDAC
Related Pathways
Chromatin/Epigenetic, DNA Damage/DNA Repair
Bioactivity
KPZ560, a potent HDAC 1 and HDAC 2 inhibitor, exhibits IC50 values of 12 nM and 68 nM, respectively. This compound enhances spine density in mouse granule neuron dendrites and inhibits growth in the MCF-7 breast cancer cell line [1].
Smiles
O=C(NC=1C=C(C=CC1N)C=2SC=CC2)C=3C=CC(=CC3)C=4N=NN(C4)CS(=O)(=O)C=5C=CC=CC5
Molecular Formula
C26H21N5O3S2
Molecular Weight
515.61
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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