KY386
Product Specifications
CAS Number
2787598-01-8
Target
Others|||DNA/RNA Synthesis
Related Pathways
DNA Damage/DNA Repair|||Others|||Cell Cycle/Checkpoint
Bioactivity
KY386 is a potent and selective DHX33 helicase inhibitor with an IC50 value of 19 nM. It demonstrates significant anti-cancer activity in DHX33-overexpressing U251-MG cell strain, achieving an IC50 of 20 nM, and exhibits moderate metabolic stability [1].
Smiles
N#CC=1C=C(SC1N2C(=CC(C(=O)NC3=NC=4C=CC(OC)=CC4N3)=C2C)C)C
Molecular Formula
C21H19N5O2S
Molecular Weight
405.47
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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