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Mal-PEG8-Phe-Lys-PAB-Exatecan

Product Specifications

CAS Number

2679821-44-2

Target

Drug-Linker Conjugates for ADC|||Topoisomerase

Related Pathways

DNA Damage/DNA Repair|||Antibody-drug Conjugate/ADC Related

Bioactivity

Compound 15, Mal-PEG8-Phe-Lys-PAB-Exatecan, is an antibody-drug conjugate (ADC) comprised of the degradable linker Mal-PEG8-Phe-Lys-PAB and the cytotoxic agent Exatecan [1].

Smiles

N(C(OCC1=CC=C(NC([C@@H](NC([C@H](CC2=CC=CC=C2)NC(CCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCN3C(=O)C=CC3=O)=O)=O)=O)CCCCN)=O)C=C1)=O)[C@@H]4C5=C6C(C=7N(C6)C(=O)C8=C(C7)[C@](CC)(O)C(=O)OC8)=NC=9C5=C(CC4)C(C)=C(F)C9

Molecular Formula

C73H92FN9O20

Molecular Weight

1434.56

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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