MC-GGFG- (7ethanol-10NH2-11F-Camptothecin)

Product Specifications

CAS Number

2873460-72-9

Target

Drug-Linker Conjugates for ADC

Related Pathways

Antibody-drug Conjugate/ADC Related

Bioactivity

MC-GGFG- (7ethanol-10NH2-11F-Camptothecin) (compound 141) is a protease-cleavable drug-linker conjugate utilized in antibody-drug conjugates (ADCs), featuring an MC-GGFG linker that allows for enzymatic cleavage [1].

Smiles

C(O)C1=C2C(C=3N(C2)C(=O)C4=C(C3)[C@@](CC)(O)C(=O)OC4)=NC=5C1=CC(NC(CNC([C@H](CC6=CC=CC=C6)NC(CNC(CNC(CCCCCN7C(=O)C=CC7=O)=O)=O)=O)=O)=O)=C(F)C5

Molecular Formula

C46H47FN8O12

Molecular Weight

922.91

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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