MFN2 agonist-1

MFN2 agonist-1 (B-A/l) effectively induces mitochondrial fusion and counteracts mitochondrial clumping [formation of static mitochondrial aggregates], reinstating mitochondrial movement in cultured mouse neurons deficient in mitofusin 2 (MFN2) and harboring the CMT2A-associated MFN2 T105M mutation.