MS6105
Product Specifications
CAS Number
2891709-58-1
Target
PROTACs
Related Pathways
PROTAC
Bioactivity
MS6105 is a chimeric LDH protein hydrolysis-targeted PROTAC that degrades LDHA and LDHB efficiently, with its activity contingent on both time and the ubiquitin-proteasome system, exhibiting anticancer properties [1]. Additionally, as a click chemistry reagent possessing an Alkyne group, MS6105 can partake in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with Azide-bearing molecules.
Smiles
C(C1=C(CC2CC2)N(N=C1C3=CC(C#CCCCCNC(CCCCCCCCCCCC(N[C@H](C(=O)N4[C@H](C(NCC5=CC=C(C=C5)C6=C(C)N=CS6)=O)C[C@@H](O)C4)C(C)(C)C)=O)=O)=CC=C3)C7=NC(C(O)=O)=CS7)C8=CC=C(S(N)(=O)=O)C=C8
Molecular Formula
C65H81N9O9S3
Molecular Weight
1228.59
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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