NBI-961
Product Specifications
CAS Number
2225902-98-5
Target
Apoptosis|||Others|||MAPK|||Serine Protease
Related Pathways
Apoptosis|||Others|||Proteases/Proteasome|||MAPK
Bioactivity
NBI-961, a potent NEK2 inhibitor, suppresses proteasomal degradation and effectively induces G2/mitosis arrest and apoptosis within diffuse large B cell lymphoma (DLBCL) cells [1].
Smiles
O=C(N)C=1SC(=CC1OC(C=2C=CC=CC2C(F)(F)F)C)C3=CN=C4C=C(C=CN43)C=5C=NN(C5)CCN(C)C
Molecular Formula
C28H27F3N6O2S
Molecular Weight
568.61
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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