NBI-961

Product Specifications

CAS Number

2225902-98-5

Target

Apoptosis|||Others|||MAPK|||Serine Protease

Related Pathways

Apoptosis|||Others|||Proteases/Proteasome|||MAPK

Bioactivity

NBI-961, a potent NEK2 inhibitor, suppresses proteasomal degradation and effectively induces G2/mitosis arrest and apoptosis within diffuse large B cell lymphoma (DLBCL) cells [1].

Smiles

O=C(N)C=1SC(=CC1OC(C=2C=CC=CC2C(F)(F)F)C)C3=CN=C4C=C(C=CN43)C=5C=NN(C5)CCN(C)C

Molecular Formula

C28H27F3N6O2S

Molecular Weight

568.61

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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