NF (N-Me) GA (N-Me) IL
Product Specifications
CAS Number
409085-42-3
Bioactivity
NF (N-Me) GA (N-Me) IL is a biologically active peptide, representing a modified segment (amino acids 22 to 27) of the human islet amyloid polypeptide (hIAPP) sequence NFGAIL. This modification includes N-methylations at G24 and I26, transforming the amyloidogenic and cytotoxic nature of the original sequence into a non-amyloidogenic and non-cytotoxic variant. Moreover, the peptide maintains the ability to bind with high affinity to full-length hIAPP, effectively inhibiting its fibril formation.
Smiles
[C@H](CC1=CC=CC=C1)(C(N(CC(N[C@H](C(N([C@H](C(N[C@@H](CC(C)C)C(O)=O)=O)[C@H](CC)C)C)=O)C)=O)C)=O)NC([C@H](CC(N)=O)N)=O
Molecular Formula
C32H51N7O8
Molecular Weight
661.79
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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