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NMB-1

Product Specifications

CAS Number

2843557-76-4

Bioactivity

NMB-1, a conopeptide analogue, selectively inhibits sustained mechanically activated currents in sensory neurons with an IC50 of 1 μM, attenuating mechanical pain. It is utilized in research pertaining to hearing and pressure-evoked pain [1] [2].

Smiles

C([C@@H](C(N[C@H](C(N[C@@H]1C(=O)N[C@@]2(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@]([C@H](CC)C)(C(=O)N3[C@](C(=O)N[C@@](CSSC2)(C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC4=CN=CN4)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC5=CC=CC=C5)C(=O)N[C@@H](CC6=CC=CC=C6)C(=O)N[C@H](C(N)=O)CSSC1)[H])(CCC3)[H])[H])[H])=O)CCCNC(=N)N)=O)NC([C@@H](NC([C@H](CC7=CC=CC=C7)N)=O)CC(N)=O)=O)C=8C=9C(NC8)=CC=CC9

Molecular Formula

C111H164N36O21S4

Molecular Weight

2466.98

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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