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NOX2-IN-2

Product Specifications

CAS Number

2648709-79-7

Target

Others, NADPH

Related Pathways

Others, Metabolism

Bioactivity

NOX2-IN-2 (compound 33) is a potent inhibitor of NOX2, disrupting the p47phox-p22phox protein-protein interaction with a dissociation constant (Ki) of 0.24 μM, and effectively suppressing reactive oxygen species (ROS) production from NOX2 in cellular contexts [1].

Smiles

N1=NN(C=C1COC=2C=CC3=NC(N)=CC=C3C2)CCOCCOC=4C=CC5=NC(N)=CC=C5C4

Molecular Formula

C25H25N7O3

Molecular Weight

471.51

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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