NOX2-IN-2
Product Specifications
CAS Number
2648709-79-7
Target
Others|||NADPH
Related Pathways
Others|||Metabolism
Bioactivity
NOX2-IN-2 (compound 33) is a potent inhibitor of NOX2, disrupting the p47phox-p22phox protein-protein interaction with a dissociation constant (Ki) of 0.24 ?M, and effectively suppressing reactive oxygen species (ROS) production from NOX2 in cellular contexts [1].
Smiles
N1=NN(C=C1COC=2C=CC3=NC(N)=CC=C3C2)CCOCCOC=4C=CC5=NC(N)=CC=C5C4
Molecular Formula
C25H25N7O3
Molecular Weight
471.51
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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