Ontorpacept
Product Specifications
CAS Number
2131089-46-6
Target
Others
Related Pathways
Others
Bioactivity
Ontorpacept (TTI-621) is a soluble fusion protein comprising the N-terminal (1-118) of human SIRP? fused to the Fc region of human IgG1. This N-terminal (1-118) segment serves as the binding domain for CD47, an inhibitor of macrophage-mediated phagocytosis. As a checkpoint inhibitor that blocks CD47, ontorpacept exhibits antitumor activity [1].
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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