PARG-IN-4

Product Specifications

CAS Number

2988890-20-4

Target

Apoptosis, Poly (ADP-ribose) Glycohydrolase (PARG)

Related Pathways

Apoptosis, Cell Cycle/Checkpoint

Purity

0.9851

Bioactivity

PARG-IN-4 (compound A) is an orally active and cell-membrane permeable PARG inhibitor (EC50=1.9 nM) that inhibits tumour growth in mice with antitumour activity.

Smiles

S(NC1(C)CC1)(=O)(=O)C=2C=C3C(=C(C2)N4C[C@H](C)N[C@@H](C)C4)C=NN3C=5SC(C(F)F)=NN5

Molecular Formula

C20H25F2N7O2S2

Molecular Weight

497.59

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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