PARG-IN-4
Product Specifications
CAS Number
2988890-20-4
Target
Apoptosis, Poly (ADP-ribose) Glycohydrolase (PARG)
Related Pathways
Apoptosis, Cell Cycle/Checkpoint
Purity
0.9851
Bioactivity
PARG-IN-4 (compound A) is an orally active and cell-membrane permeable PARG inhibitor (EC50=1.9 nM) that inhibits tumour growth in mice with antitumour activity.
Smiles
S(NC1(C)CC1)(=O)(=O)C=2C=C3C(=C(C2)N4C[C@H](C)N[C@@H](C)C4)C=NN3C=5SC(C(F)F)=NN5
Molecular Formula
C20H25F2N7O2S2
Molecular Weight
497.59
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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