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PH14

Product Specifications

Target

HDAC, PI3K, Apoptosis

Related Pathways

PI3K/Akt/mTOR signaling, Chromatin/Epigenetic, DNA Damage/DNA Repair, Apoptosis

Bioactivity

PH14, a dual PI3K/HDAC inhibitor, demonstrates potent inhibition with IC50 values of 20.3 nM for PI3Kα and 24.5 nM for HDAC3. It exhibits antiproliferative effects and induces apoptosis in Jeko-1 cells, making it a valuable tool in cancer research, including lymphoma studies [1].

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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