What is the catalog number for PI3Kα-IN-14?

The catalog number for PI3Kα-IN-14 is T81469.

What sizes are available for PI3Kα-IN-14?

PI3Kα-IN-14 is available in the following size(s): 5 mg, 50 mg.

How many pack sizes does PI3Kα-IN-14 come in?

PI3Kα-IN-14 is available in 2 different pack sizes.

Is PI3Kα-IN-14 in stock?

PI3Kα-IN-14 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures PI3Kα-IN-14?

PI3Kα-IN-14 is manufactured by Molfinity.

What is the estimated delivery time for PI3Kα-IN-14?

Estimated delivery time for PI3Kα-IN-14 is approximately 10 business day(s), depending on your location.

PI3Kα-IN-14

Product Specifications

Target

PI3K, Apoptosis

Related Pathways

PI3K/Akt/mTOR signaling, Apoptosis

Bioactivity

PI3Kα-IN-14 (compound F8), a potent PI3Kα inhibitor, exhibits an IC50 value of 0.14 nM and significantly reduces mitochondrial membrane potential, leading to G1 phase cell cycle arrest and apoptosis in U87-MG cells. It also shows substantial antiproliferative effects against various tumor cell lines, including PC-3 (IC50 of 0.28 μM), HCT-116 (IC50 of 0.57 μM), and U87-MG (IC50 of 1.37 μM) [1].