PL-3994
Product Specifications
CAS Number
952295-80-6
Bioactivity
PL-3994, a natriuretic peptide receptor-A (NPR-A) agonist resistant to neutral endopeptidase, functions as a bronchodilator, eliciting a concentration-dependent relaxation of pre-contracted guinea-pig trachea, evidenced by an IC50 of 42.7 nM [1].
Smiles
C([C@H](CC1=CC=C(O)C=C1)NC(=O)[C@H]2NC(=O)[C@H](CO)NC(=O)[C@]([C@H](CC)C)(NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](CCCC)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@H](CC3=CC=CC=C3)NC(=O)[C@H](CC4=CN=CN4)NC(=O)[C@@H](NC(CCCCCC)=O)CSSC2)[H])(=O)N5[C@@H](CCCNC(=N)N)C(=O)N[C@@H](C(N)=O)C5
Molecular Formula
C82H127N27O20S2
Molecular Weight
1875.19
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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