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PNMT-IN-1

Product Specifications

Target

Adrenergic Receptor|||Others

Related Pathways

Neuroscience|||GPCR/G Protein|||Others

Bioactivity

PNMT-IN-1 (inhibitor 4) is a selective second generation inhibitor [1] of phenylethanolamine N-methyltransferase (PNMT), exhibiting a Ki value of 1.2 nM and an IC50 value of 81 nM. Additionally, it disrupts the activity of DNMT1 and DNMT3b, with IC50 values of 61 ?M and 17 ?M, respectively, and antagonizes the action of epinephrine.

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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