RGD-targeted Proapoptotic Peptide

RGD-Targeted Proapoptotic Peptide is a peptide that preferentially binds to integrins at sites of tumor angiogenesis through its C-terminal RGD-4C sequence (ACDCRGDCFC) .

C([C@@H]1NC(=O)[C@]2(NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@](CSSC2)(NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC([C@H](C)N)=O)CSSC[C@@H](C(NCC(NCC(N[C@@H](C(N[C@@H](C(N[C@H](C(N[C@@H](C(N[C@@H](C(N[C@@H](C(N[C@@H](C(N[C@@H](C(N[C@@H](C(N[C@@H](C(N[C@@H](C(N[C@@H](C(N[C@@H](C(N[C@H](CCCCN)C(O)=O)=O)C)=O)CC(C)C)=O)CCCCN)=O)C)=O)CC(C)C)=O)CCCCN)=O)CCCCN)=O)C)=O)CC(C)C)=O)CCCCN)=O)C)=O)CC(C)C)=O)CCCCN)=O)=O)=O)NC1=O)[H])[H])C3=CC=CC=C3