RIPK1-IN-17
Product Specifications
CAS Number
3033385-59-7
Target
RIP kinase
Related Pathways
Apoptosis|||NF-?B
Purity
0.9522
Bioactivity
RIPK1-IN-17 is a dual inhibitor of RIPK1 and RIPK3 that specifically inhibits necrosis by inhibiting phosphorylation of RIPK1, RIPK3 and MLKL, protecting mice from hypothermia and death in a tnf-induced inflammation model.
Smiles
FC1=C(NC(CC2=CC=CC(OC(F)(F)F)=C2)=O)C=C(C3=CC=C(N=C(NC(C4CC4)=O)S5)C5=C3)C=C1
Molecular Formula
C26H19F4N3O3S
Molecular Weight
529.51
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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