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RIPK1-IN-17

Product Specifications

CAS Number

3033385-59-7

Target

RIP kinase

Related Pathways

Apoptosis|||NF-?B

Purity

0.9522

Bioactivity

RIPK1-IN-17 is a dual inhibitor of RIPK1 and RIPK3 that specifically inhibits necrosis by inhibiting phosphorylation of RIPK1, RIPK3 and MLKL, protecting mice from hypothermia and death in a tnf-induced inflammation model.

Smiles

FC1=C(NC(CC2=CC=CC(OC(F)(F)F)=C2)=O)C=C(C3=CC=C(N=C(NC(C4CC4)=O)S5)C5=C3)C=C1

Molecular Formula

C26H19F4N3O3S

Molecular Weight

529.51

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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