RIPK3-IN-4
Product Specifications
CAS Number
2304617-58-9
Target
RIP kinase
Related Pathways
Apoptosis, NF-κB
Bioactivity
RIPK3-IN-4 (Compound 42) is a RIPK3 inhibitor that mitigates necroptosis, inflammatory responses, and HK-2 cell damage. It alleviates acute kidney injury by attenuating Cisplatin- and I/R-induced kidney damage, along with associated inflammatory responses and necroptosis [1].
Smiles
O=C(NC=1C=CC=C(Br)C1)NC2=CC(OC=3C=CC=4N=C(SC4C3)NC(=O)C5CC5)=CC=C2F
Molecular Formula
C24H18BrFN4O3S
Molecular Weight
541.39
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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