SEH/FLAP-IN-1
Product Specifications
Target
Epoxide Hydrolase, FLAP
Related Pathways
Metabolism, Immunology/Inflammation
Bioactivity
SEH/FLAP-IN-1 (Compound 46A) serves as a dual inhibitor targeting both sEH and FLAP, effectively suppressing 5-LOX product formation with an EC50 of 11 nM in SACM-stimulated PBMCs, inhibiting sEH activity (EC50: 18 nM), and reducing thromboxane production. This compound is utilized in the study of inflammatory diseases [1].
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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