SH491
Product Specifications
Target
Others
Related Pathways
Others
Bioactivity
SH491 (Compound 33) serves as an antiosteoporosis agent, effectively inhibiting RANKL-induced osteoclast differentiation in bone-marrow-derived monocytes (BMMs) with an IC50 of 11.8 nM. Additionally, SH491 suppresses the expression of genes and proteins related to osteoclastogenesis, specifically TRAP, CTSK, MMP-9, and ATPase v0d2 [1].
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
K6444404 1.0 µg DNA
Nusap1 sgRNA CRISPR Lentivector (Rat) (Target 3)
Sign In for Pricing
View Details 
MBS1075231-01 0.02 mg (E-Coli)
Recombinant Geobacter sp. UPF0042 nucleotide-binding protein Geob_2284 (Geob_2284)
Sign In for Pricing
View Details MBS1075231-02 0.02 mg (Yeast)
Recombinant Geobacter sp. UPF0042 nucleotide-binding protein Geob_2284 (Geob_2284)
Sign In for Pricing
View Details MBS1075231-03 0.1 mg (E-Coli)
Recombinant Geobacter sp. UPF0042 nucleotide-binding protein Geob_2284 (Geob_2284)
Sign In for Pricing
View Details MBS1075231-04 0.1 mg (Yeast)
Recombinant Geobacter sp. UPF0042 nucleotide-binding protein Geob_2284 (Geob_2284)
Sign In for Pricing
View Details MBS1075231-05 0.02 mg (Baculovirus)
Recombinant Geobacter sp. UPF0042 nucleotide-binding protein Geob_2284 (Geob_2284)
Sign In for Pricing
View Details