TGR5 Receptor Agonist 4
Product Specifications
CAS Number
1872436-42-4
Target
Others, GPCR19
Related Pathways
GPCR/G Protein, Others
Bioactivity
TGR5 Receptor Agonist 4, a selective agonist for the Bile Acid Receptor (TGR5), exhibits potent activity with an EC50 of 2 nM for human TGR5 (hTGR5) and 3 nM for mouse TGR5 (mTGR5) . It is notably involved in mediating hypoglycemic and weight loss effects [1].
Smiles
C(OCC1=C(OC)C=CC=C1)(=O)C=2[C@@H](CC(=O)N(C[C@H]3CCCO3)C2C)C=4C=CC(Cl)=NC4
Molecular Formula
C25H27ClN2O5
Molecular Weight
470.95
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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