Tubulin polymerization-IN-56
Product Specifications
CAS Number
2966790-98-5
Target
Apoptosis, Others, Microtubule Associated
Related Pathways
Apoptosis, Others, Cytoskeletal Signaling
Bioactivity
Tubulin Polymerization-IN-56 (compound 8l), an indazole derivative, potently inhibits tubulin polymerization by targeting the colchicine site, which induces cell cycle arrest and apoptosis. Additionally, this compound diminishes cell migration and significantly inhibits tumor growth in vivo [1].
Smiles
Cl.N1=CC(=CC=C1C)C=2C=CC=3C=NN(C4=CC(OC)=C(OC)C(OC)=C4)C3C2
Molecular Formula
C22H22ClN3O3
Molecular Weight
411.88
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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