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VEGFR2/HDAC1-IN-1

Product Specifications

Target

HDAC, Apoptosis, VEGFR

Related Pathways

DNA Damage/DNA Repair, Angiogenesis, Chromatin/Epigenetic, Tyrosine Kinase/Adaptors, Apoptosis

Bioactivity

VEGFR2/HDAC1-IN-1 (compound 13) is a potent dual inhibitor of VEGFR-2 and HDAC, with IC50 values of 57.83 nM for VEGFR-2 and 9.82 nM for HDAC. It arrests the cell cycle at the S and G2 phases and induces apoptosis in HeLa cells, demonstrating an anti-angiogenic effect [1].

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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