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VRT-534

Product Specifications

CAS Number

926664-32-6

Target

Others|||Gap Junction Protein

Related Pathways

Others|||Cytoskeletal Signaling

Bioactivity

VRT-534 is a compound that selectively targets connexin 26 (Cx26), demonstrating dose-responsive binding to both wild-type (WT) Cx26 and the mutant Cx26 K188N, with EC50 values of 19 ?M and 5 ?M, respectively. It has potential applications in research concerning hearing impairment [1].

Smiles

C(NC=1SC([C@H](C2=C(Cl)C=CC=C2)N3C[C@H](O)CC3)=CN1)(=O)C4(CC4)C=5C=C6C(=CC5)OCO6

Molecular Formula

C25H24ClN3O4S

Molecular Weight

497.99

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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