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ZIKV-IN-6

Product Specifications

Target

Others, Anti-infection, DNA/RNA Synthesis

Related Pathways

Others, Cell Cycle/Checkpoint, Microbiology/Virology, DNA Damage/DNA Repair

Bioactivity

ZIKV-IN-6 (compound 22) is a direct inhibitor of the Zika virus (ZIKV) that binds to its RNA-dependent RNA polymerase (RdRp), obstructing viral RNA synthesis mediated by the ZIKV NS5 protein. The compound exhibits low cytotoxicity (CC50 >50 μM) and mitigates excessive inflammatory response and pyroptosis [1].

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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