Thalidomide-NH- (CH2) 2-NH2 TFA
Product Specifications
Target
E3 Ligase Ligand-Linker Conjugate|||Others|||Autophagy|||Apoptosis
Related Pathways
Autophagy|||PROTAC|||Others|||Apoptosis
Bioactivity
Thalidomide-NH- (CH2) 2-NH2 TFA, an alkyl-modified derivative of Thalidomide, functions as a Cereblon ligand to recruit CRBN proteins and serves as a crucial intermediate in the synthesis of CRBN-based PROTAC molecules targeting the SHP2 protein.
Smiles
NCCNC1=C2C(=O)N(C3C(=O)NC(=O)CC3)C(=O)C2=CC=C1.OC(=O)C(F)(F)F
Molecular Formula
C17H17F3N4O6
Molecular Weight
430.34
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Product Datasheet
https://www.targetmol.com/attachment/DataSheet/123792458663329880/T80646
CAS Number
1957235-67-4
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![Mouse Monoclonal Ribophorin II Antibody (OTI1G9) [DyLight 405]](https://cdn.genprice.uk/genprice/genprice5.png)
