Thalidomide-NH- (CH2) 2-NH2 TFA
Product Specifications
CAS Number
1957235-67-4
Target
E3 Ligase Ligand-Linker Conjugate, Others, Autophagy, Apoptosis
Related Pathways
Autophagy, PROTAC, Others, Apoptosis
Bioactivity
Thalidomide-NH- (CH2) 2-NH2 TFA, an alkyl-modified derivative of Thalidomide, functions as a Cereblon ligand to recruit CRBN proteins and serves as a crucial intermediate in the synthesis of CRBN-based PROTAC molecules targeting the SHP2 protein.
Smiles
NCCNC1=C2C(=O)N(C3C(=O)NC(=O)CC3)C(=O)C2=CC=C1.OC(=O)C(F)(F)F
Molecular Formula
C17H17F3N4O6
Molecular Weight
430.34
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS7037130-01 0.02 mg
Recombinant Clostridium acetobutylicum UPF0059 membrane protein CA_C0950 (CA_C0950)
Sign In for Pricing
View Details MBS7037130-02 0.1 mg
Recombinant Clostridium acetobutylicum UPF0059 membrane protein CA_C0950 (CA_C0950)
Sign In for Pricing
View Details MBS7037130-03 5x 0.1 mg
Recombinant Clostridium acetobutylicum UPF0059 membrane protein CA_C0950 (CA_C0950)
Sign In for Pricing
View Details 
14419151 3x 1.0 µg DNA
C2orf61 CRISPR All-in-one AAV vector set (with saCas9)(Human)
Sign In for Pricing
View Details 
A07705-1-Cy3 100 µg/Vial
Anti-Proteasome 20S beta 6/PSMB6 Antibody Picoband®, Cy3 Conjugate
Sign In for Pricing
View Details