Brolucizumab
Product Specifications
CAS Number
1531589-13-5
Target
VEGFR
Related Pathways
Tyrosine Kinase/Adaptors, Angiogenesis
Purity
0.9967
Bioactivity
Brolucizumab (DLX1008) is a single-chain variable fragment (scFv) anti-VEGF-A antibody exhibiting an exceptionally low picomolar binding affinity (K D = 1.05 pM) . through its potent blockade of vascular endothelial growth factor A (VEGF-A), Brolucizumab effectively reduces pathological neovascularization and vascular leakage within the macula and is under investigation for the treatment of neovascular (wet) age-related macular degeneration (AMD) .
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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