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N-myristoyl-RKRTLRRL

Product Specifications

CAS Number

152246-40-7

Target

PKC

Related Pathways

Chromatin/Epigenetic|||Cytoskeletal Signaling

Bioactivity

N-myristoyl-RKRTLRRL is a compound that impedes the binding of protein kinase C (PKC) substrates and inhibits calcium (Ca2+) - and phosphatidylserine (PS) -dependent phosphorylation of histones, exhibiting an IC50 of 5 ?M. Additionally, it demonstrates an inhibitory effect on histone phosphorylation with an IC50 of 80 ?M [1] [2].

Smiles

[C@H](C(N[C@H](C(N[C@@H](CC(C)C)C(O)=O)=O)CCCNC(=N)N)=O)(NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CCCCCCCCCCCCC)=O)CCCNC(=N)N)=O)CCCCN)=O)CCCNC(=N)N)=O)[C@@H](C)O)=O)CC(C)C)=O)CCCNC(=N)N

Molecular Formula

C60H117N21O11

Molecular Weight

1308.71

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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