N-myristoyl-RKRTLRRL
Product Specifications
CAS Number
152246-40-7
Target
PKC
Related Pathways
Chromatin/Epigenetic|||Cytoskeletal Signaling
Bioactivity
N-myristoyl-RKRTLRRL is a compound that impedes the binding of protein kinase C (PKC) substrates and inhibits calcium (Ca2+) - and phosphatidylserine (PS) -dependent phosphorylation of histones, exhibiting an IC50 of 5 ?M. Additionally, it demonstrates an inhibitory effect on histone phosphorylation with an IC50 of 80 ?M [1] [2].
Smiles
[C@H](C(N[C@H](C(N[C@@H](CC(C)C)C(O)=O)=O)CCCNC(=N)N)=O)(NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CCCCCCCCCCCCC)=O)CCCNC(=N)N)=O)CCCCN)=O)CCCNC(=N)N)=O)[C@@H](C)O)=O)CC(C)C)=O)CCCNC(=N)N
Molecular Formula
C60H117N21O11
Molecular Weight
1308.71
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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