β-Endorphin (1-27) (human)
Product Specifications
CAS Number
76622-84-9
Target
Opioid Receptor
Related Pathways
Neuroscience, Endocrinology/Hormones, GPCR/G Protein
Bioactivity
β-Endorphin (1-27) (human) is an opioid antagonist that selectively binds to μ-, δ-, and κ-opioid receptors, with dissociation constants (Kis) of 5.31, 6.17, and 39.82 nM, respectively. It inhibits analgesia induced by both β-Endorphin and etorphine [1][2].
Smiles
C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC1=CC=CC=C1)NC(CNC(CNC([C@H](CC2=CC=C(O)C=C2)N)=O)=O)=O)=O)CCSC)=O)[C@@H](C)O)=O)CO)=O)CCC(O)=O)=O)CCCCN)=O)CO)=O)CCC(N)=O)=O)[C@@H](C)O)(=O)N3[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC4=CC=CC=C4)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC5=CC=C(O)C=C5)C(O)=O)=O)C)=O)CC(N)=O)=O)CCCCN)=O)[C@H](CC)C)=O)[C@H](CC)C)=O)C)=O)CC(N)=O)=O)CCCCN)=O)=O)CC(C)C)=O)[C@@H](C)O)=O)C(C)C)=O)CC(C)C)=O)CCC3
Molecular Formula
C139H217N33O40S
Molecular Weight
3022.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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