Kurtoxin
Product Specifications
Target
Sodium Channel, Calcium Channel
Related Pathways
Metabolism, Membrane transporter/Ion channel
Bioactivity
Kurtoxin is a selective Cav3 (T-type) voltage-gated Ca2+ channel gating inhibitor with a dissociation constant (Kd) of 15 nM for the Cav3.1 (α1G T-type) Ca2+ channel. It exhibits high-affinity interactions with native neuronal high-threshold L-type, N-type, and P-type Ca2+ channels in both central and peripheral neurons and displays cross-reactivity with the voltage-gated Na+ channel [1].
Molecular Formula
C324H478N94O90S8
Molecular Weight
7386.36
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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