α-Conotoxin GIC
Product Specifications
CAS Number
757236-92-3
Target
AChR
Related Pathways
Neuroscience
Bioactivity
α-Conotoxin GIC is a selective and potent antagonist of the α3β2 nicotinic acetylcholine receptor, exhibiting an inhibition constant (IC50) of 1.1 nM [1].
Smiles
O=C1N2[C@@](CCC2)(C(=O)N[C@@H](C)C(=O)N[C@@]3(C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC4=CN=CN4)C(=O)N[C@@]([C@H](CC)C)(C(=O)N[C@H](C(N)=O)CSSC[C@@](C(=O)N[C@@H](CO)C(=O)N[C@H]1CC5=CN=CN5)(NC(=O)[C@@H](NC(CN)=O)CSSC3)[H])[H])[H])[H]
Molecular Formula
C61H92N24O20S4
Molecular Weight
1609.79
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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