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α-Conotoxin GIC

Product Specifications

Target

AChR

Related Pathways

Neuroscience

Bioactivity

?-Conotoxin GIC is a selective and potent antagonist of the ?3?2 nicotinic acetylcholine receptor, exhibiting an inhibition constant (IC50) of 1.1 nM [1].

Smiles

O=C1N2[C@@](CCC2)(C(=O)N[C@@H](C)C(=O)N[C@@]3(C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC4=CN=CN4)C(=O)N[C@@]([C@H](CC)C)(C(=O)N[C@H](C(N)=O)CSSC[C@@](C(=O)N[C@@H](CO)C(=O)N[C@H]1CC5=CN=CN5)(NC(=O)[C@@H](NC(CN)=O)CSSC3)[H])[H])[H])[H]

Molecular Formula

C61H92N24O20S4

Molecular Weight

1609.79

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Product Datasheet

https://www.targetmol.com/attachment/DataSheet/123792363825922064/T80478

CAS Number

757236-92-3

Available Sizes

Curated Selection

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