α-Conotoxin RgIA

α-Conotoxin RgIA (α-RgIA), a specific α9α10 nAChR antagonist, is derived from the venom of Conus regius and has applications in researching neurological diseases [1].

O=C1[C@]2(N(C(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@]3(NC(=O)[C@@H](NC(CN)=O)CSSC[C@](NC(=O)[C@H](CCCNC(=N)N)N1)(C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC4=CC=C(O)C=C4)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(N[C@@H](CCCNC(=N)N)C(O)=O)=O)CSSC3)[H])[H])CCC2)[H]