ω-Conotoxin CVIB
Product Specifications
CAS Number
325164-09-8
Target
Sodium Channel
Related Pathways
Membrane transporter/Ion channel
Bioactivity
ω-Conotoxin CVIB is an antagonist of non-selective N- and P/Q-type voltage-gated calcium channels (VGCCs) . It inhibits depolarization-activated whole-cell VGCC currents in dorsal root ganglion (DRG) neurons, exhibiting a pIC50 of 7.64 [1].
Smiles
C([C@@H]1NC(=O)[C@H](CCSC)NC(=O)[C@]([C@@H](C)O)(NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@]2(NC(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)CNC(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CSSC[C@@]3(NC(=O)[C@@](NC(=O)[C@H](CC(O)=O)NC1=O)(CSSC[C@@H](C(N)=O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@](CSSC2)(NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CCCNC(=N)N)NC3=O)[H])[H])[H])[H])[H])C4=CC=C(O)C=C4
Molecular Formula
C102H173N41O32S7
Molecular Weight
2710.18
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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