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Ceratotoxin-1

Product Specifications

Target

Sodium Channel

Related Pathways

Membrane transporter/Ion channel

Bioactivity

Ceratotoxin-1 (CcoTx1) is a peptide toxin that functions as an inhibitor of various voltage-gated sodium channel subtypes. It selectively inhibits Nav1.1/β1, Nav1.2/β1, Nav1.4/β1, and Nav1.5/β1 with IC50 values of 523 nM, 3 nM, 888 nM, and 323 nM, respectively. Additionally, Ceratotoxin-1 is known to inhibit Nav1.8/β1 [1].

Molecular Formula

C172H256N52O50S6

Molecular Weight

4044.58

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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