Jingzhaotoxin-V
Product Specifications
Target
Sodium Channel
Related Pathways
Membrane transporter/Ion channel
Bioactivity
Jingzhaotoxin-V, a 29-residue polypeptide from Chilobrachys jingzhao spider venom, selectively inhibits tetrodotoxin-resistant and tetrodotoxin-sensitive sodium currents in rat dorsal root ganglion neurons, with IC50 values of 27.6 nM and 30.2 nM, respectively. Furthermore, it suppresses Kv4.2 potassium currents in Xenopus laevis oocytes, with an IC50 of 604.2 nM [1].
Molecular Formula
C157H243N47O37S7
Molecular Weight
3605.36
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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