TFLLRNPNDK-NH2
Product Specifications
CAS Number
145229-90-9
Target
Thrombin
Related Pathways
Proteases/Proteasome
Bioactivity
TFLLRNPNDK-NH2 is a biologically active peptide and a thrombin receptor activating peptide (TRAP) . As a PAR-1 agonist, it reversibly binds to PAR-1, mimicking the 'tethered ligand' created by thrombin through proteolytic substrate cleavage. It also induces increased liquid and protein permeability, similar to thrombin's effect.
Smiles
C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC1=CC=CC=C1)NC([C@H]([C@@H](C)O)N)=O)=O)CC(C)C)=O)CC(C)C)=O)CCCNC(=N)N)=O)CC(N)=O)(=O)N2[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCCCN)C(N)=O)=O)CC(O)=O)=O)CC(N)=O)=O)CCC2
Molecular Formula
C54H89N17O15
Molecular Weight
1216.39
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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