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TFLLRNPNDK-NH2

Product Specifications

CAS Number

145229-90-9

Target

Thrombin

Related Pathways

Proteases/Proteasome

Bioactivity

TFLLRNPNDK-NH2 is a biologically active peptide and a thrombin receptor activating peptide (TRAP) . As a PAR-1 agonist, it reversibly binds to PAR-1, mimicking the 'tethered ligand' created by thrombin through proteolytic substrate cleavage. It also induces increased liquid and protein permeability, similar to thrombin's effect.

Smiles

C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC1=CC=CC=C1)NC([C@H]([C@@H](C)O)N)=O)=O)CC(C)C)=O)CC(C)C)=O)CCCNC(=N)N)=O)CC(N)=O)(=O)N2[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCCCN)C(N)=O)=O)CC(O)=O)=O)CC(N)=O)=O)CCC2

Molecular Formula

C54H89N17O15

Molecular Weight

1216.39

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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