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Garvicin KS, GakA

Product Specifications

CAS Number

2098351-24-5

Target

Antibacterial

Related Pathways

Microbiology/Virology

Bioactivity

Garvicin KS (GarKS) is a bacteriocin composed of a 34 amino acid peptide, GakA, and two additional peptides, GakB and GakC. GakA alone has been found to reduce fibroblast viability and proliferation. When combined with GakB, GakA forms an effective duo that exhibits notable peptide stability, antimicrobial potency, and an influence on fibroblast viability and proliferation. Among the Garvicin KS peptides, GakB is the most effective against MSSA, with minimum inhibitory concentration (MIC) values ranked as GakB > GakC > GakA [1].

Smiles

C([C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@H](CC=1C=2C(NC1)=CC=CC2)NC(CNC([C@@H](NC([C@H](CC=3C=4C(NC3)=CC=CC4)NC([C@@H](NC([C@@H](NC(CNC(CNC(CNC([C@@H](NC([C@@H](NC(CNC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@H](CCSC)N)=O)=O)C)=O)[C@H](CC)C)=O)[C@H](CC)C)=O)CCCCN)=O)C)=O)=O)C)=O)CCCCN)=O)[C@H](CC)C)=O)C(C)C)=O)=O)CCCCN)=O)=O)[C@H](C)C)=O)CC(C)C)=O)=O)=O)=O)C)=O)CO)=O)=O)CC(C)C)=O)=O)=O)CC(N)=O)=O)C(C)C)=O)=O)CCC(O)=O)=O)CCCCN)=O)[C@H](CC)C)=O)C(N[C@@H](CCCCN)C(O)=O)=O)C=5C=6C(NC5)=CC=CC6

Molecular Formula

C161H259N43O39S

Molecular Weight

3453.11

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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