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Huwentoxin I

Product Specifications

CAS Number

769973-37-7

Target

Sodium Channel, Calcium Channel

Related Pathways

Metabolism, Membrane transporter/Ion channel

Bioactivity

Huwentoxin I (HWTX-I) is a peptide toxin that inhibits voltage-gated sodium channels and N-type calcium channels. It effectively blocks sodium channels in rat hippocampus and cockroach dorsal unpaired median (DUM) neurons, with IC50 values of 66.1 nM and 4.80 nM, respectively [1].

Molecular Formula

C161H246N48O44S6

Molecular Weight

3750.36

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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