BDS-I
Product Specifications
CAS Number
207621-38-3
Target
Potassium Channel
Related Pathways
Membrane transporter/Ion channel
Bioactivity
BDS-I, a marine toxin derived from Anemonia sulcata, functions as a selective inhibitor of the potassium channel, specifically targeting Kv3.4. It impedes the Aβ1-42-induced augmentation of Kv3.4 activity, caspase-3 activation, and distortion of nuclear morphology in NGF-differentiated PC-12 cells. Moreover, BDS-I effectively counteracts the cell death induced by the Aβ peptide [1].
Molecular Formula
C210H297N57O56S6
Molecular Weight
4708.34
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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